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Acute Care

CLOTS Clots in Legs or TEDs after Stroke MRC Prof Martin Dennis. University of Edinburgh

COSSACS Continue or Stop post-Stroke Antihypertensives Collaborative Study The Health Foundation Dr Tom Robinson, University of Leicester

ECASS 3 is a placebo controlled trial of alteplase (rt-PA) in acute ischaemic hemispheric stroke where thrombolysis is initiated between 3 and 4.5 hours after stroke onset, Boehringer Ingelheim NIH link

ENOS Efficacy of Nitric Oxide in Stroke trial BUPA Foundation, MRC Prof Philip Bath, University of Nottingham

IST-3 Third International Stroke Trial UK Medical Research Council, the Health Foundation, the Stroke Association Prof Peter Sandercock, University of Edinburgh

STICH II Surgical Trial in Intracerebral Haemorrhage MRC Prof David Mendelow, University of Newcastle

Prevention

ACES Asymptomatic Carotid Emboli Study British Heart Foundation Prof Hugh Markus, St George's University of London

ACST-2 Asymptomatic Carotid Surgery Trial-2 surgery vs stenting, Alison Halliday, St George's University of London

B-SWISS British Siblings with Ischaemic Stroke Study The Stroke Association Prof Hugh Markus, St George's University of London

CADISS Cervical Artery Dissection in Stroke Study The Stroke Association Prof John Norris, St George's University of London

DNA Lacunar resource The Wellcome Trust Prof Hugh Markus, St George's University of London

SLESS - South London Ethnicity and Stroke Study, Prof Hugh Markus, St George's University of London

ICSS International Carotid Stenting Study The Stroke Association Prof Martin Brown, University College London

PERFORM Prevention of cerebrovascular and cardiovascular Events of ischaemic origin with teRutroban in patients with a history oF ischaemic strOke or tRansient ischaeMic attack. Servier Research and Development. Chief investigator K. Lees, Glasgow University.

VITATOPS VITAmins TO Prevent Stroke Study MRC Prof Kennedy Lees, University of Glasgow

Primary Care

Home BP Monitoring Study - Community based trial of home blood pressure monitoring with nurse-led telephone support in patients with stroke or TIA recently discharged from hospital, Dr Pippa Oakeshott, St Georges, London

Rehabilitation RCTs

MTS dose (upper limb) Mobilisation and tactile stimulation to enhance upper limb recovery after stroke: Phase I investigation of acceptable dose, efficacy and underlying mechanisms The Stroke Association Prof Val Pomeroy St Georges, London

FST (lower limb)The effects of functional strength training on weakness and function of the lower limb after stroke. Health Foundation Prof Val Pomeroy St Georges, London

TRACS A cluster RCT of a structured training programme for caregivers of in-pts after stroke MRC Dr Anne Forster, University of Bradford

Single Centre Studies 

TBS Study Enhancing the effect of physical therapy for motor impairment after stroke with Theta Burst Stimulation (TBS)